Syndactyly is the term used to describe joined fingers or toes.
Abnormal heart function
Abnormal heart (cardiac) function specifically associated with an unusual electrical activity.
The heart takes longer to ‘recharge’ between beats (known as a prolonged QT interval), which can lead to an irregular heart beat rate or rhythm (arrhythmias).
Abnormal heart structure
Abnormal heart structure includes conditions such as:
- PDA (Patent Ductus Arteriosus) – a persistent opening between the two major blood vessels leading from the heart
- TOF (Tetralogy of Fallot) – a combination of 4 congenital abnormalities, including:
- ventricular septal defect (VSD)
- pulmonary stenosis
- a misplaced aorta
- thickened right ventricular wall (right ventricular hypertrophy)
- ASD (Atrial Septal Defect) – a hole in the wall between the two upper chambers of the heart
Neuronal developmental delays
Developmental delays refer to physical, social and mental difficulties. These can include:
- ASD (autism spectrum disorder)
- ADD (attention deficit disorder)
- ADHD (attention deficit hyperactivity disorder)
- OCD (obsessive compulsive disorder)
Immunodeficiencies affect the immune system’s ability to fight diseases in the body. This can result in frequent upper and lower respiratory tract infections.
Too much or not enough of the endocrine hormone can lead to pancreatic, adrenal and thyroid concerns.
Effects on smooth muscle
This most commonly leads to gastrointestinal issues such as constipation and irritable bowel syndrome.
Effects on skeletal muscle
This may result in including low muscle tone, also know as hypotonia.
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